Best Science & Space Museums in the USA
Discover the best science & space museums in the USA, including the Museum of Science and Industry in Chicago. Explore the highlights and plan your next educational adventure.

Science museums captivate minds by transforming complex concepts into interactive experiences. Whether you're a curious traveler or a lifelong learner, these institutions offer a journey through innovation, discovery, and wonder. Here's a curated list of some of the world's most remarkable science museums.
From powerful planetariums to hands-on labs and real spacecraft, science and space museums in the USA spark curiosity for all ages. Whether you're passionate about astronomy, robotics, or climate science, these institutions bring big ideas to life with interactive exhibits, immersive theaters, and once-in-a-lifetime artifacts.
Here’s a guide to the best science and space museums in the United States — where education meets exploration
Griffin Museum of Science and Industry - Chicago, IL
Located in Chicago's Hyde Park neighborhood, the Museum of Science and Industry (MSI) is one of the largest science museums in the Western Hemisphere. Housed in the historic Palace of Fine Arts from the 1893 World's Columbian Exposition, MSI offers over 2,000 exhibits across 75 halls.
Highlights
- Coal Mine: Descend into a recreated coal mine to learn about mining technology.
- U-505 Submarine: Explore the only German U-boat captured during WWII on display in the U.S.
- Science Storms: Witness natural phenomena like tornadoes and lightning.
- Henry Crown Space Center: Discover space exploration artifacts, including the Apollo 8 command module.
📍 Location: 5700 S Lake Shore Dr, Chicago, IL
Museum of Science - Boston, MA
Situated along the Charles River, Boston's Museum of Science is a hub for STEM education. With over 700 interactive exhibits, it caters to visitors of all ages.
Highlights
- Theater of Electricity: Experience live lightning demonstrations.
- Planetarium: Explore the cosmos through immersive shows.
- Live Animal Center: Interact with various species and learn about their habitats.
📍 Location: 1 Science Park, Boston, MA
Kennedy Space Center Visitor Complex – Cape Canaveral, FL
If you're a fan of NASA, this is the holy grail. The Kennedy Space Center offers up-close access to real space shuttles, rockets, and astronauts.
Highlights:
- Space Shuttle Atlantis on display
- Apollo/Saturn V Center
- Rocket Garden & launch pad tours
📍 Location: Space Commerce Way, Merritt Island, FL
Smithsonian National Air and Space Museum – Washington, D.C.
This free-entry museum on the National Mall is home to some of humanity’s most important flight and space artifacts.
Highlights:
- Wright Flyer (1903)
- Apollo 11 Command Module
- Full-scale Hubble Space Telescope model
📍 Location: 600 Independence Ave SW, Washington, DC
U.S. Space & Rocket Center – Huntsville, AL
Known as “Rocket City,” Huntsville hosts this museum adjacent to NASA’s Marshall Space Flight Center.
Highlights:
- Saturn V Rocket (one of three in existence)
- Space Camp programs
- Moon landing simulations & Mars missions
📍 Location: One Tranquility Base, Huntsville, AL
California Science Center – Los Angeles, CA
This LA-based science center combines ecosystems, life science, and space tech, including the permanent home of Space Shuttle Endeavour.
Highlights:
- Space Shuttle Endeavour
- Air & Space Gallery
- Rotating IMAX & science exhibits
📍 Location: 700 Exposition Park Dr, Los Angeles, CA
Whether you’re looking to walk beneath a Saturn V rocket or explore dark matter through hands-on simulations, these museums offer more than exhibits — they deliver unforgettable experiences. From Chicago to Cape Canaveral, each destination bridges imagination and scientific discovery.